1. Quatrefolic® (6S)-5-methyltetrahydrofolate glucosamine salt
  2. Vitamin B12 (as Methylcobalamin)

Take one tablet daily or as directed by the physician

  • Helps to reduce the risk of neural tube defects when taken daily at least 3 months prior to becoming pregnant and during early pregnancy
  • Helps to support normal early fetal development( brain and spinal cord)
  • Helps to form red blood cells and reduce the risk of megaloplastic anemia .
  • Reduce the risk of CVS disorders as it decreases the risk of hyperhomocysteinaemia .
  • Helps to support the bodies ability to metabolize neutrients
  • Helps in energy metabolism
  • Helps to support immune function of the immune system
  • Helps to prevent folate & vitamin B 12 defeciency

 Cobafolic is the only product in the Egyptian market that contains the fully active forms of: folate as (Quatrefolic® ) & vitamin B12 (as Methylcobalamin) .

Methylcobalmin is the active form of vitamin B12 that doesn’t require any further metabolism.

Quatrefolic® is Gnosis patented new generation of folate , namely : (6S)-5-methyltetrahydrofolate glucosamine salt .

The innovative glucosamine salt is considered the fourth generation fully active form of folate that  able to overcome the existing limits of previous generations related to stability and solubility.

 Quatrefolic® has significant advantages over previous folate generations while maintaining the same biological properties of 5-methyltetrahydrofolate. This remarkable step forward is attributed to :

  • Improved solubility

Quatrefolic® is 100 time more soluble than the calcium salt and defined as water soluble, a significant opportunity for improving bioavailability, whereas the calcium salt version is defined as sparingly soluble.

  • Improved bioavailability

As quatrefolic doesnot need any further metabolism .

  • Guaranteeing a safety and high-quality stable profile by choosing glucosamine as natural compound naturally present in the body.



Carton box containing 30 film coated tablets .

Keep the drug out of reach of children.

Store at temperature not exceeding 30° C.